Current MLB Players:Trevor Williams
- High School - Rancho Bernardo High School
- College - Arizona State University
- Selected in the 2nd round of the 2013 draft by the Miami Marlins
- MLB debut was September 7, 2016 with the Pittsburgh Pirates
- Currently plays with the Washington Nationals and previously played with the Pittsburgh Pirates, Chicago Cubs and New York Mets
Sean Bouchard
- High School - Cathedral Catholic
- College - UCLA
- Selected in the 9th round of the 2017 draft by the Colorado Rockies
- MLB debut was on June 19, 2022 with the Colorado Rockies
Alexander "Alika" Williams
- High School - Rancho Bernardo High School
- Selected in the 32nd round of the 2017 draft by the New York Yankees but didn't sign and enrolled in college
- College - Arizona State University
- Selected in the 37th round of the 2020 draft by the Tampa Bay Rays
- MLB debut was on July 25, 2023 with the Pittsburgh Pirates
Retired: Cole "Hollywood" Hamels
- High School - Rancho Bernardo High School
- Selected in the 1st round of the 2002 draft by the Phildelphia Phillies
- MLB debut was on May 12, 2006 with the Philadelphia Phillies
- Previously played for the Philadelphia Phillies, Texas Rangers, Chicago Cubs and Atlanta Braves
- Career Milestones: 4-time All Star, World Series Champion, World Series MVP, and 2 no-hitters (1 combined)